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This is, in fact, similar to get_top_hvgs(). The only difference is that HVGs are first combined from all SingleCellExperiment objects in sce_list and consequently, top HVGs are selected.

Usage

sce_int_combine_hvgs(
  sce_list,
  hvg_selection_value = 0,
  hvg_metric_fit_name = "hvg_metric_fit",
  hvg_combination = c("hvg_metric", "intersection", "union", "all"),
  hvg_selection = c("top", "significance", "threshold")
)

Arguments

sce_list

A named list of SingleCellExperiment objects.

hvg_selection_value, hvg_selection

See get_top_hvgs().

hvg_metric_fit_name

A character scalar: name of a list item with HVG data in metadata().

hvg_combination

See sce_int_import_fn().

Value

A named list of combined HVG data.