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For Harmony integration, the "harmony" reduced dims are used as an input to scran::buildSNNGraph(); otherwise PCA is used.

Usage

sce_int_clustering_df_fn(
  sce_int_pca_df,
  snn_k = 10,
  snn_type = "rank",
  snn_clustering_method = c("walktrap", "louvain"),
  BPPARAM = BiocParallel::SerialParam()
)

Arguments

sce_int_pca_df

(input target) A tibble.

snn_k, snn_type, snn_clustering_method

See sce_int_raw_snn_clustering_fn().

BPPARAM

A BiocParallel::BiocParallelParam object.

Value

A modified sce_int_pca_df with appended SingleCellExperiment object with computed clustering. Output target: sce_int_clustering_df

The following items of metadata() of each integrated SingleCellExperiment object are added or modified:

  • int_cluster_snn_k, int_cluster_snn_type, int_cluster_snn_method: taken from parameters of the integration method.